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| Product Name | Anaphase-Promoting Complex Inhibitor, TAME (TAME Hydrochloride) |
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| Description | Purity ~95% (HPLC). TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC50=12uM. Formula: C14H22N4O4S • HCl Molecular Weight: 378.87 Solubility: DMSO (50mg/ml) |
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| Size | 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217180 |
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| Order / More Info | Anaphase-Promoting Complex Inhibitor, TAME (TAME Hydrochloride) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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