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| Product Name | PrCP, Active, Recombinant, Human |
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| Description | Purified (~50%). PrCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Source: Recombinant corresponding to aa31-496 from human PrCP, fused to His-tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~53kD Applications: Suitable for the cleavage of C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PrCP, Active, Recombinant, Human (Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PCP) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137361 |
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| Order / More Info | PrCP, Active, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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