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| Product Name | NFkB, p50, Recombinant, Human, GST-Tag |
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| Description | Purified by Glutathione agarose chromatography. ≥ 90%, determined by SDS-PAGE and Coomassie blue staining. This gene encodes a 105kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kD protein. The 105kD protein is a Rel protein-specific transcription inhibitor and the 50kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Source: N-terminal GST-tagged, recombinant human NFkB, p50 subunit (delta434- |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NFkB, p50, Recombinant, Human, GST-Tag (delta434-969) (NF-kB, Nuclear Factor kappa B p50 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B cells 1, NFkB1, DKFZp686C01211, DNA Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, NF-kB, Nuclear Factor kappa B DNA Binding Subunit) |
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| Gene, Accession, CAS # | Accession: NM_003998.2, SwissProt: P19838 |
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| Catalog # | N2301-52G |
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| Order / More Info | NFkB, p50, Recombinant, Human, GST-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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