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| Product Name | NFKB3, Recombinant, Human, aa1-210, GST-Tag (Transcription Factor p65 Protein) |
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| Description | Purity ~90% (SDS-PAGE). NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with ot |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 |
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| Gene, Accession, CAS # | SwissProt: Q04206 |
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| Catalog # | 374408 |
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| Order / More Info | NFKB3, Recombinant, Human, aa1-210, GST-Tag (Transcription Factor p65 Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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