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| Product Name | Matrix Metalloproteinase 3, Recombinant, Human, His-Tag (MMP3, Stromelysin-1, Transin-1) |
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| Description | Purity ~95% (SDS-PAGE). MMP-3 enzyme is also known as Stromelysin-1 or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk. MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta. Source: Recombinant protein corresponding to a proform of the human MMP3 [Tyr18-Cys477 (Lys45Glu)], fused to His-tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~52kD Biological Activity: Measured by its ability to cleave the fluorogenic peptide substrate, |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299449 |
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| Order / More Info | Matrix Metalloproteinase 3, Recombinant, Human, His-Tag (MMP3, Stromelysin-1, Transin-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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