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| Product Name | GR 127935 Hydrochloride |
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| Description | Purity ~98% (HPLC). A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behaviour in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Solubility: H2O Primary Target: 5-HT1B/1D |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217397 |
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| Order / More Info | GR 127935 Hydrochloride from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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