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| Product Name | MCP-2, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Monocyte chemotactic protein MCP-2 is a C-C chemokine. It shares over 60% amino acid identity with MCP-1 and MCP- 3 and has about 30% identity with other C-C chemokines MIP-1 alpha, RANTES, and MIP-1 beta. MCP-2 is chemotactic for and activates a wide variety of inflammatory cells, and its spectrum of action on leukocytes is similar to that of MCP-3, including monocytes, T lymphocytes, natural killer cells, basophils, mast cells, and eosinophils, but differs from MCP-1, which is not active on eosinophils. MCP-2 has been proposed to interact with multiple C-C chemokine receptors, including those used by MCP- 1 and MCP-3. However, since leukocytes express a multiplicity of chemokine receptors with promiscuous binding and functional properties, it is difficult to identify the receptors used by a given ligand on these cells. Source: Recombinant protein corresponding to human MCP-2 expressed in E. coli. Molecular Weight: ~9kD Biological Activity: The ED50 was determined by the dose-dependen |
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| Size | 25ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MCP-2, Recombinant, Human (Monocyte Chemotactic Protein-2, MCP2, HC14, C-C Motif chemokine 8, Monocyte Chemoattractant Protein-2, CCL8) |
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| Gene, Accession, CAS # | SwissProt: P80075 |
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| Catalog # | 500237 |
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| Order / More Info | MCP-2, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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