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| Product Name | MCP-4, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils, monocytes, and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells, and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis. The expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy. The recombinant construct corresponds to the ``short-chain'' of CCL13 spanning aa24-98. Source: Recombinant protein corresponding to human MCP-4 expressed in E. coli. Molecular Weight: ~9kD Biological Activity: Determined by its ability to chemoattract human monocytes us |
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| Size | 25ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MCP-4, Recombinant, Human (Monocyte Chemotactic Protein 4, NCC-1, C-C motif Chemokine 13, Small-Inducible Cytokine A13, MCP4, NCC1, SCYA13 Monocyte Chemoattractant Protein-4, CCL13) |
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| Gene, Accession, CAS # | SwissProt: Q99616 |
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| Catalog # | 500240 |
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| Order / More Info | MCP-4, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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