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| Product Name | M-CSF, Recombinant, Mouse (Macrophage Colony-stimulating Factor, Csfm) |
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| Description | Purity ~98% (SDS-PAGE, HPLC). M-CSF (Macrophage colony-stimulating factor) is a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells. Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor).A genetic defect in M-CSF is responsible for osteopetrosis in mice (op/op), which are severely deficient in mature macrophages and have a restricted capacity for bone remodelling. Source: Recombinant protein corresponding to mouse M-CSF expressed in E. coli. Molecular Weight: ~36.4kD (156aa) Activity: The ED50 was determined by the dose dependent stimulation of the proliferation of murine M-NSF-60 cells is 1x10e6units/mg |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 214990 |
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| Order / More Info | M-CSF, Recombinant, Mouse (Macrophage Colony-stimulating Factor, Csfm) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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