| 产品详情 |
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| Product Name | PKD2, Active, Recombinant, Human (Protein Kinase D2) |
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| Description | Purity ~80% (SDS-PAGE). PKD2 is a novel phorbol ester- and growth factor-stimulated serine/threonine kinase that contains two cysteine-rich motifs at the N terminus, a pleckstrin homology domain, and a catalytic domain (1). It exhibits the strongest homology to the serine/threonine protein kinases PKD/PKCmu and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. The PKD family of enzymes have been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation (2).PKD2 can be activated by phorbol esters both in vivo and in vitro but also by gastrin via the cholecystokinin/CCK(B) receptor in human gastric cancer cells stably transfected with the CCK(B)/gastrin receptor (AGS-B cells) (3). Gastrin-stimulated PKD2 activation involves a heterotrimeric G alpha(q) protein as well as the activa |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | pdk-2, pdk 2, Active PKD2, PKD2, human PKD2, active kinase, active kinases, PKD, recombinant PKD2, recombinant PKD, kinase activity assay, protein kinase |
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| Gene, Accession, CAS # | PKD2, Gene ID: 5311, SwissProt: Q13563 |
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| Catalog # | 220174 |
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| Order / More Info | PKD2, Active, Recombinant, Human (Protein Kinase D2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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