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| Product Name | IL-29, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE, HPLC). IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor beta (IL10RB) and interleukin 28 receptor alpha. IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumor activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues. Source: Recombinant protein corresponding to 181aa from human IL-29, expressed in E. coli. Mol |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-29, Recombinant, Human (Interleukin-29, IFN-Lambda 1, Interferon-Lambda 1, Cytokine ZCYTO21, IL29, IFNL1, ZCYTO21) |
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| Gene, Accession, CAS # | IL29, Gene ID: 282618, SwissProt: Q8IU54 |
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| Catalog # | 219938 |
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| Order / More Info | IL-29, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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