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| Product Name | IL12, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is natually produced by activated monocytes/macrophage cells, B lymphocytes, and connective tissue type mast cells in response to antigenic stimulation. IL12 is involved in the differentiation of naive T cells into Th1 cells and can stimulate the growth and function of T cells. IL12 also plays an important role in the activities of natural killer cells and T lymphocytes. Recombinant Human IL12 is expressed in human 293 cells as a heterodimeric cytokine composed of two glycosylated and disulfide-linked subunits (p40 cysteine-linked to p35) with a molecular mass of 57kD. Source: Recombinant protein corresponding to human IL12 expressed in HEK293. Molecular Weight: ~57kD Biological Activity: The EC50 as determined by the dose-dependent release of IFN-gamma from the human NK92 cell line in presence of 20ng/mL rIL-2 was found to be ≤2ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL12, Recombinant, Human (IL-12, NKSF, CTL Maturation Factor, TCMF, Cytotoxic Lymphocyte Maturation Factor, CLMF, TSF, Edodekin-Alpha) |
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| Gene, Accession, CAS # | Gene ID: 3592, SwissProt: P29459 |
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| Catalog # | 500105 |
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| Order / More Info | IL12, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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