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| Product Name | IL24, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). IL-24 (melanoma differentiation-associated gene-7 [mda-7]), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in the immune system has not been defined but studies have indicated a role for IL-24 in inflammatory conditions such as psoriasis. The tumor suppressor effects of IL-24 include inhibition of angiogenesis, sensitization to chemotherapy, and p38 mitogen-activated protein kinase (MAPK)-mediated apoptosis. Current knowledge on the regulation of IL-24 expression is sparse. The melanoma differentiation- associated gene-7 (mda-7) was discovered through subtraction hybridization of cDNA libraries prepared from melanoma cells. As mda-7 shares considerable structural and sequence homology with IL-10 cytokine family members it was recognized as a member of this family and renamed interleukin-24 (IL-24). IL-24 signals through a heterodimeric receptor complex consisting of the IL-20R-beta sub |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL24, Recombinant, Human (IL-24, Melanoma Differentiation-Associated Gene 7 Protein, MDA-7, Suppression of Tumorigenicity 16 Protein, MDA7, ST16, Interleukin-24) |
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| Gene, Accession, CAS # | SwissProt: Q13007 |
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| Catalog # | 500140 |
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| Order / More Info | IL24, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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