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| Product Name | IL18, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Also known as interferon-gamma-inducing factor (IGIF) and IL-1gamma, IL18 is a cytokine that bears structural similarities with members of the IL-1 family of proteins. IL18 is natively synthesized as a proform that gets processed by caspase-1 to generate the bioactive form of IL18. IL18 is one of the pro-inflammatory cytokines that is expressed by a variety of immune and non-immune cells. The activities of IL18 appear to be species specific. An important function of IL18 is the regulation of functionally distinct subsets of T-helper cells required for cell mediated immune responses. IL18 functions as a growth and differentiation factor for Th1 cells and is known to up-regulate the FAS ligand mediated cytotoxic activity of murine natural killer cells. IL18 also partakes in a complex regulatory circuit involved in causing cell death by apoptosis. Source: Recombinant protein corresponding to human IL18 expressed in E. coli. Molecular Weight: ~18.5kD Biological Activity: The ED50 as determ |
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| Size | 25ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL18, Recombinant, Human (IL-18, Interferon Gamma-Inducing Factor, IFN-Gamma-Inducing Factor, Interleukin-1 Gamma, IL-1 Gamma, Interleukin-18) |
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| Gene, Accession, CAS # | SwissProt: Q14116 |
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| Catalog # | 500118 |
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| Order / More Info | IL18, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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