| 产品详情 |
| Edit |   |
|---|
| Product Name | IL27, Recombinant, Human |
|---|
| Description | Purity ~95% (SDS-PAGE). IL27 is a cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL-17 producing helper T cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. Recombinant Human IL-27 expressed in human 293 cells as a non-covalently bonded heterodimer cytokine composed of IL27p28 (25kD) and glycosylated EB13 (30kD). Source: Recombinant pro |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | IL27, Recombinant, Human (Interleukin-27 Subunit Alpha, IL-27 Subunit Alpha, IL-27-A, IL27-A, p28, Interleukin-27) |
|---|
| Gene, Accession, CAS # | SwissProt: Q8NEV9 |
|---|
| Catalog # | 500142 |
|---|
| Price | |
|---|
| Order / More Info | IL27, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|