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| Product Name | IL3, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). IL-3 is produced mainly by T cells following cell activation by antigens and mitogens, but also by keratinocytes, natural killer cells, mast cells, endothelial cells, and monocytes. The analysis of bacterial-derived recombinant IL-3 shows that glycosylation is not required for the activity of IL-3. IL-3 sequences are evolutionarily less well conserved. Human and murine IL-3 show approximately 29 % homology at the protein level while murine and rat IL-3 show approximately 54% homology. IL-3-alpha and IL-3-beta are two isoforms of rat IL-3. IL-3 receptors are expressed on macrophages, mast cells, eosinophils, megakaryocytes, basophils, bone marrow progenitor cells, and various myeloid leukemia cells. IL-3/receptor complexes have a Kdis of 10-9 - 10-10 M. Binding of IL-3 to its receptor causes specific phosphorylation of a 150kD membrane glycoprotein. Source: Recombinant protein corresponding to human IL3 expressed in CHO cells. Molecular Weight: ~15kD Biological Activity: The ED50 was de |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL3, Recombinant, Human (IL-3, Hematopoietic Growth Factor, Mast Cell Growth Factor, MCGF, Multipotential Colony-Stimulating Factor, P-Cell-Stimulating Factor, Interleukin-3) |
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| Gene, Accession, CAS # | SwissProt: P08700 |
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| Catalog # | 500149 |
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| Order / More Info | IL3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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