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| Product Name | IL4, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). IL4 is produced mainly by a sub-population of activated T helper cells which also secrete IL5 and IL6. The biological activities of IL4 are mediated by a specific receptor, the extracellular domain of which is related to the receptors for EPO, IL6, and the beta chain of the IL-2 receptor. IL4 participates in several B-cell activation processes as well as of other cell types. A co-stimulator of DNA-synthesis, IL4 induces the expression of class II MHC molecules on resting B-cells, enhances both secretion and cell surface expression of IgE and IgG1, and also regulates the expression of the low affinity Fc receptor for IgE on both lymphocytes and monocytes. Pre-treatment of macrophages with IL4 prevents the production of IL1, TNF-alpha and prostaglandins in response to activation of the cells by bacterial endotoxins or IFN-gamma. Source: Recombinant protein corresponding to human IL4 expressed in E. coli. Molecular Weight: ~15kD Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL4, Recombinant, Human (IL-4, BCGF, BCDF, B Cell Stimulating Factor, BSF-1, Lymphocyte Stimulatory Factor 1, Interleukin-4) |
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| Gene, Accession, CAS # | SwissProt: P05112 |
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| Catalog # | 500164 |
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| Order / More Info | IL4, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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