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| Product Name | IL6, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). IL-6 is a pleiotropic cytokine that participates in a wide variety of biological functions such as acute phase response, inflammation, hematopoiesis, bone metabolism and cancer. While produced mainly by stimulated monocytes, fibroblasts and endothelial cells, IL-6 is also known to be produced by macrophages, T cells, B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells and keratinocytes, upon stimulation. Unlike murine IL-6 which is inactive on human cells, both human and murine IL-6 are equally active on murine cells. The IL-6 receptor is a strongly glycosylated protein of 80kD and a length of 449aa (designated CD126). Recombinant human IL-6 is a 21kD, glycosylated protein that contains two disulfide bridges. Source: Recombinant protein corresponding to human IL6 expressed in CHO cells. Molecular Weight: ~21kD Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 7TD1 c |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL6, Recombinant, Human (IL-6, IL-6/26kD Protein, B Cell Stimulatory Factor 2, BSF-2, B Cell Differentiation Factor, BCDF, CTL Differentiation Factor, CDF, Hybridoma Growth Factor, Interferon Beta-2, IFN-Beta-2, IFNB2, HPGF, HSF, MGI-2, Interleukin-6) |
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| Gene, Accession, CAS # | SwissProt: P05231 |
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| Catalog # | 500172 |
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| Order / More Info | IL6, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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