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| Product Name | IL-12, Recombinant, Human, aa57-253 |
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| Description | Purity ~98% (SDS-PAGE). Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40kD (p40) subunit and a 35kD (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and a |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-12, Recombinant, Human, aa57-253 (Interleukin-12, IL-12p70, IL-12p75, Cytotoxic Lymphocyte Maturation Factor, CLMF, NKSF, Natural Killer Cell Stimulatory Factor, TSF, T-cell Stimulatory Factor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207231 |
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| Order / More Info | IL-12, Recombinant, Human, aa57-253 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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