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| Product Name | IL12, Recombinant, Human, aa23-328/aa23-219, His-Tag (Interleukin 12 (Subunit beta/alpha)) |
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| Description | Purity ~85% (SDS-PAGE). IL12 is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. It is a disulfide-linked heterodimer composed of the 40kD cytokine receptor like subunit and a 35kD subunit. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. IL12 has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Source: Recombinant protein corresponding to human IL12, fused to His-tag at C-terminus, expressed in Insect cells. Molecular Weight: ~34.6kD (p40) & ~23.3kD (p35) (306aa & 203aa) The heterodimeric IL12 has a predicted molecular weight of ~57.9kD (509aa). Applications: Suitable for use in SDS-PAGE. |
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| Size | 20ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000873 (IL12A, p35), NP_002178 (IL12B, p40) |
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| Catalog # | 218253 |
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| Order / More Info | IL12, Recombinant, Human, aa23-328/aa23-219, His-Tag (Interleukin 12 (Subunit beta/alpha)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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