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| Product Name | IL29, Recombinant, Human, aa21-200, His-SUMO-Tag (Interleukin-29) |
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| Description | Purity ~90% (SDS-PAGE). Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. Source: Recombinant protein corresponding to aa21-200 from human IL29, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~36.0kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cytokine Zcyto21 Interleukin-29, IL-29 |
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| Gene, Accession, CAS # | SwissProt: Q8IU54 |
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| Catalog # | 373817 |
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| Order / More Info | IL29, Recombinant, Human, aa21-200, His-SUMO-Tag (Interleukin-29) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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