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| Product Name | MIP-3, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). The chemokine MIP-3 beta is a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells, and natural killer cells. It might, therefore, play an important role in the trafficking of T cells in the thymus and migration of T and B cells to secondary lymphoid organs. Furthermore, MIP-3 beta has been recently shown to mediate rapid adhesion of naive CD4(+) T lymphocytes to activated endothelial cells supporting the role of this chemokine in regulation of lymphocyte homing. MIP-3 beta acts through CC chemokine receptor 7 (CCR7). The chemokines Lkn-1 and MIP-3 alpha are also lymphocyte attractants, although compared with MIP- 3 beta, their promigratory effect on lymphocytes is less intensive and their chemotactic activity is more promiscuous. Lkn-1 attracts monocytes, lymphocytes, and eosinophils via the chemokine receptors CCR1 and CCR3. MIP-3 alpha exhibits promigratory effects on lymphocytes, neutrophils, and immature dendritic cells via the CCR6 receptor. Sourc |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MIP-3, Recombinant, Mouse (CCL19, C-C Motif Chemokine 19, MIP3, Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine, EBI1 Ligand Chemokine, ELC, Small-Inducible Cytokine A19) |
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| Gene, Accession, CAS # | SwissProt: O70460 |
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| Catalog # | 500268 |
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| Order / More Info | MIP-3, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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