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| Product Name | Cripto-1, Recombinant, Human |
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| Description | Purified by immunoaffinity chromatography. Cripto is the founding member of the epidermal growth factor-CriptoFRL1Cryptic (EGF-CFC) family of signaling proteins that function in cancer and various developmental processes. These developmental processes include: formation of the germ layers and dorsal organizer, specification of anterior-posterior and left-right axes, and differentiation of heart muscle.1, 2 Other members of the EGF-CFC family include Cryptic, Xenopus FRL-1 and zebrafish OEP (one-eyed pinhead). Overall sequence identity between members of the family is low, but they do share several common domains: a variant EGF-like motif, a novel conserved cysteine-rich domain (called CFC domain), and a C-terminal hydrophobic region. Most EGF-CFC members have a glycosyl-phosphatidylinositol (GPI) anchoring site at the C-terminus and exist as extracellular membrane-anchored proteins. However, naturally-occurring soluble isoforms also exist. Human Cripto shares 66% and 28% amino acid ide |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Cripto-1, Recombinant, Human (Epidermal Growth Factor-Like Cripto Protein CR1, TDGF-1, Teratocarcinoma-Derived Growth Factor 1, CFC-2) |
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| Gene, Accession, CAS # | Accession: NP_003203 |
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| Catalog # | C7922-10D |
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| Order / More Info | Cripto-1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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