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| Product Name | Procathepsin K, Recombinant (Cathepsin K, Cathepsin O, Cathepsin X, Cathepsin O2, CTSO2, CTSO) |
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| Description | Purity ~95% (SDS-PAGE). Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is synthesized as an inactive proenzyme (35.1kD) that is converted to its mature active form (23.6kD) by proteolytic cleavage of its 99aa propeptide domain. The in vitro processing of procathepsin K to mature cathepsin K is autocatalytic. Source: Recombinant protein corresponding to human Procathepsin K. Biological Activity: The specific activity is >1000mU/mg (1U = 1umole/min/mg) as measured by Cathepsin K Activity Assay Kit. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169724 |
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| Order / More Info | Procathepsin K, Recombinant (Cathepsin K, Cathepsin O, Cathepsin X, Cathepsin O2, CTSO2, CTSO) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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