| 产品详情 |
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| Product Name | Procathepsin K, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Cathepsin K is a member of the papain cysteine proteinase family and has been identified as the predominant proteinase responsible for the resorption of the bone matrix. The enzyme cleaves proteins such as collagen type I, collagen type II and osteonectin and therefore plays a role in bone remodeling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is synthesized as an inactive proenzyme (35.1kD) that is converted to its mature active form (23.6kD) by proteolytic cleavage of its 99aa propeptide domain. The in vitro processing of procathepsin K to mature cathepsin K is autocatalytic. Source: Recombinant protein corresponding to mouse Procathepsin K, expressed in E. coli. Molecular Weight: ~35.5kD |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Procathepsin K, Recombinant, Mouse (Cathepsin O, Cathepsin K, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2) |
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| Gene, Accession, CAS # | CATK, Gene ID: 1513, SwissProt: P43235 |
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| Catalog # | 220189 |
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| Order / More Info | Procathepsin K, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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