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| Product Name | TNFRSF10B, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). TNFRSF10B is a member of the TNFR superfamily and is a cell surface receptor that is involved in apoptosis. It contains an intracellular death domain and can be activated by binding to either membrane-anchored or soluble TRAIL/Apo2L. Diseases associated with TNFRSF10B include squamous cell carcinoma, head and neck and oral cavity cancer. Among its related pathways are Akt Signaling and Akt Signaling. It is closely related to TRAIL R1/DR4, sharing 55% amino acid sequence identity. Source: Recombinant protein corresponding to human TNFRSF10B expressed in E. coli. Molecular Weight: ~15kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.2ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 50ug, 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFRSF10B, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member 10B, Death Receptor 5, TRAIL Receptor 2, TRAIL-R2, CD262, TNF-Related Apoptosis-Inducing Ligand Receptor 2) |
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| Gene, Accession, CAS # | SwissProt: O14763 |
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| Catalog # | 500508 |
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| Order / More Info | TNFRSF10B, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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