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| Product Name | TNFRSF1B, Recombinant, Human, aa27-203, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 1B) |
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| Description | Purity ~90% (SDS-PAGE). Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Source: Recombinant protein corresponding to aa27-203 from human TNFRSF1B, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~46.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII,TNFR-II, p75, p80, TNF-alpha receptor, CD120bINN, Etanercept |
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| Gene, Accession, CAS # | SwissProt: P20333 |
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| Catalog # | 375623 |
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| Order / More Info | TNFRSF1B, Recombinant, Human, aa27-203, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 1B) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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