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| Product Name | WNT-1, Recombinant, Human (WNT-1 Proto-Oncogene Protein, INT1, WNT1) |
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| Description | Purity ~98% (SDS-PAGE, HPLC). Wnt-1, formerly known as int-1, is a non-glycosylated secreted protein associated with the extracellular matrix, involved in normal embryonic development and particularly linked with breast cancer. Wnt-1, which signals through binding to the Frizzled family of transmembrane receptors, was originally identified as a proto-oncogene implicated in carcinomas induced by the mouse mammary tumor virus (MMTV). Wnt-1 belongs to a family of Wnt genes involved in the dorso-ventricular development of the mesoderm during embryogenesis, with a restricted temporal and spatial pattern of expression. Source: Recombinant protein corresponding to human WNT-1, expressed in E. coli. Molecular Weight: ~38.4kD (343aa residues). Biological Activity: The ED50 was determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The expected ED50 for this effect is 1.5-2.5ng/ml in the presence of 200ng/ml of human BMP-2. Applications: Suitabl |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | WNT1, Gene ID: 7471, SwissProt: P04628 |
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| Catalog # | 215213 |
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| Order / More Info | WNT-1, Recombinant, Human (WNT-1 Proto-Oncogene Protein, INT1, WNT1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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