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| Product Name | UMPS, Recombinant, Human, aa1-480, His-Tag (Uridine 5'-monophosphate Synthase, OPRT) |
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| Description | Purity ~95% (SDS-PAGE). UMPS, also known as uridine 5'-monophosphate synthase, is a bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis. It is an indispensable component in this metabolic pathway and is a target for antimalarial and antitumor drugs. Its expression in colorectal carcinoma tissues is not correlated with the toxicities of 5-FU-based regimen, but It in the normal tissues can help predict the toxicities associated with 5-FU. Source: Recombinant protein corresponding to aa1-480 from human UMPS, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~53kD (486aa) 50-70kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000364 |
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| Catalog # | 378001 |
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| Order / More Info | UMPS, Recombinant, Human, aa1-480, His-Tag (Uridine 5'-monophosphate Synthase, OPRT) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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