| 产品详情 |
| Edit |   |
|---|
| Product Name | FER, Recombinant, Mouse, GST-Tag (Fert, Fert2, AV082135) |
|---|
| Description | Purified (~70-90%). FER is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell cell interactions. Genetic analysis using transgenic mouse models implicate FER in the regulation of inflammation and innate immunity. Fer-deficient mice displayed enhanced recruitment of leukocytes in response to local LPS challenge. FER is required for cell-cycle progression in malignant cells. Decreasing the level of FER using RNAi impeded the proliferation of prostate and breast carcinoma cells and led to their arrest at the G0/G1 phase. Source: Recombinant protein corresponding to mouse FER fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~59kD Biological Activity: The specific activity of FER was determined to be 655nmol/min/mg as per activity assay protocol. |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: NM_001037997 |
|---|
| Catalog # | 499982 |
|---|
| Price | |
|---|
| Order / More Info | FER, Recombinant, Mouse, GST-Tag (Fert, Fert2, AV082135) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|