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| Product Name | Translational Control BioAssay™ Sample Kit |
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| Description | Purified by Protein A and peptide affinity chromatography. The synthesis of new protein is a highly regulated process that allows rapid cellular responses to diverse stimuli in the absence of transcription. Initiation of protein synthesis begins after the separation of the ribosome into its 40S and 60S subunits. Different eukaryotic initiation factors (eIFs) catalyze the assembly of a functional ribosomal complex including the 40S subunit, mRNA and tRNA, and finally the 60S subunit before the first peptide bond is formed. eIF4F and p70 S6 kinase play critical roles in translational regulation. eIF4F is a complex whose functions include the recognition of the mRNA 5' cap structure (eIF4E), delivery of an RNA helicase to the 5' region (eIF4A), bridging of the mRNA and the ribosome (eIF4G), and circularization of the mRNA via interaction between eIF4G and the poly(A) binding protein (PABP). Several stimuli, including growth factors and cytokines, regulate the eIF4 complex and p70 S6 kinas |
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| Size | 6x20ul |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8263 |
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| Price | |
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| Order / More Info | Translational Control BioAssay™ Sample Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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