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| Product Name | ACES Signal Sequence BioAssay™ Kit |
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| Description | E. coli is often the host strain of first choice for the production of recombinant proteins. Despite its long and successful history, several limitations remain when the desired protein cannot be expressed in a functional state. This is often due to the inherent properties of expressing heterologous proteins in the cytoplasm. One means of overcoming these impediments is to express the protein such that it is secreted into an environment that is more conducive to correct folding and where proteolytic degradation is minimized, such as the periplasm or extracellular matrix. Periplasmic or extracellular protein export has been exploited for the production of a number of recombinant proteins. The extracellular accumulation of a target protein provides several advantages. These include: A Simplified Downstream Purification Scheme, Enhanced Biological Activity, Higher Product Stability and Solubility. Protein secretion in E. coli and other Gram-negative bacteria is an extensively reviewed sub |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 226803 |
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| Order / More Info | ACES Signal Sequence BioAssay™ Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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