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| Product Name | ANGPTL3, Recombinant, Human |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. ANGPTL-3 (Angiopoietin like protein 3) is a member of the angiopoietinfamily of structurally related proteins, characterized by a coiled N-terminaldomain and a C-terminal fibrinogen like domain. It is primarily expressed inthe liver and can exert activities related to both angiogenesis and lipidmetabolism. ANGPTL-3 inhibits lipoprotein lipase (LPL) and endothelial lipase(EL), which has the effect of increasing plasma levels of triglycerides and HDLassociated cholesterol. The fibrinogen like portion of the ANGPTL-3 protein canbind alpha-5/beta-3 integrins leading to endothelial cell adhesion and migration. Recombinant human ANGPTL-3 isa glycoprotein that migrates by SDS-PAGE analysis at an apparent molecularweight of 62kD, and contains 452aa residues including a C-terminal His tag. Biological Activity: Measured by its binding ability to recombinant alpha v beta 3 integrin in a functional ELISA. AA Sequence: SRIDQDNSSF DSLSPEPKSR FAMLDDVKIL |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ANGPTL3, Recombinant, Human (Angiopoietin-related Protein 3, Angiopoietin-5, ANG-5, Angiopoietin-like Protein 3, ANGPT5, UNQ153/PRO179) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143277 |
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| Order / More Info | ANGPTL3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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