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| Product Name | Angpt2, Recombinant, Mouse, aa19-483, His-Tag (Angiopoietin-2) |
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| Description | Purity ~90% (SDS-PAGE). Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Source: Recombinant protein corresponding to aa19-483 from mouse Angiopoietin-2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O35608 |
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| Catalog # | 372257 |
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| Order / More Info | Angpt2, Recombinant, Mouse, aa19-483, His-Tag (Angiopoietin-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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