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| Product Name | IL-24, Recombinant, Mouse, aa66-220 |
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| Description | Purity ~95% (SDSPAGE). Interleukin 24 (IL24), also known as FISP (IL-4 induced secreted protein) in mouse, and mda-7 (melanoma differentiation associated gene-7) in humans, is a member of the IL10 family of helical cytokines (1-3). The mouse IL24 gene encodes for a 181 amino acid (aa) precursor that includes a 26 aa signal sequence and an 18kD (predicted), 155aa mature segment (4). Unlike mature human IL24, which contains three potential Nlinked glycosylation sites, mouse mature IL-24 has only one. In human, both glycosylation and the presence of an intrachain disulfide bond have been found to be necessary for full activity (5). This requirement for glycosylation is unique among IL10 family members. Presumably, the same structural modifications apply to mouse IL24. Mouse IL-24 is a 27kD protein when secreted, and is active on human receptors (1, 3). Mature mouse IL-24 shares 69%, 84%, 69%, 68% and 61% aa sequence identity with human, rat, equine, canine and bovine IL-24, respec |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-24, Recombinant, Mouse, aa66-220 (Interleukin 24 , Interleukin 24, C49A, FISP, MDA-7, MOB-5, ST16) |
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| Gene, Accession, CAS # | Accession: NP_444325 |
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| Catalog # | 145705 |
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| Order / More Info | IL-24, Recombinant, Mouse, aa66-220 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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