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| Product Name | Il16, Recombinant, Mouse, aa22-287, His-Tag |
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| Description | Purity ~95%. IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20kD active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist; the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippoc |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Il16, Recombinant, Mouse, aa22-287, His-Tag (Pro-interleukin-16, Interleukin-16, IL-16, Lymphocyte Chemoattractant Factor, LCF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149786 |
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| Order / More Info | Il16, Recombinant, Mouse, aa22-287, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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