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| Product Name | IL33, Recombinant, Mouse, aa109-266, His-Tag (Interleukin-33) |
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| Description | Purity ~85% (SDS-PAGE). Interleukin 33 (IL-33) is a 32kD proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kD and C-terminal fragment of 18kD by cleavage of caspase-1. Source: Recombinant protein corresponding to aa109-266 from mouse IL33, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~18.1kD (181aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001158196 |
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| Catalog # | 218260 |
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| Order / More Info | IL33, Recombinant, Mouse, aa109-266, His-Tag (Interleukin-33) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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