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| Product Name | IL12, Recombinant, Mouse, aa23-335 (IL12b)/ aa23-215(IL12a), His-tag |
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| Description | Purity ~95% (SDS-PAGE). IL12b/IL12a, also known as interleukin 12 (subunit beta/alpha), is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. It is a key mediator of cellular-immunity and induces the differentiation of Th1 cells from precursor T helper cells. As it is associated with IL23A to form the IL-23 interleukin, it induces autoimmune inflammation and is responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Source: Recombinant protein corresponding to aa23-335 of mouse IL12b/IL12a, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~35.7kD (p40), ~22.5kD (p35) (313aa/199aa). The heterodimeric Il12 has a predicted molecular weight of 58.3kD (512aa). Molecular weight on SDS-PAGE will appear higher. Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL12, Recombinant, Mouse, aa23-335 (IL12b)/ aa23-215(IL12a), His-Tag (Interleukin 12 (Subunit Beta/Alpha), IL12b/IL12a, Il-12b/Il-12a, IL-12p40/Il-12p35, Il12p40/Il12p35, p40/p35) |
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| Gene, Accession, CAS # | Accession: NP_001290173 (Il12 beta) / NP_032377 (Il12 alpha) |
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| Catalog # | 396883 |
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| Order / More Info | IL12, Recombinant, Mouse, aa23-335 (IL12b)/ aa23-215(IL12a), His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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