| 产品名称 |
IL-24, Recombinant, Mouse, aa66-220 (Interleukin 24, C49A, FISP, MDA-7, MOB-5, ST16) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IL-24, Recombinant, Mouse, aa66-220 (Interleukin 24, C49A, FISP, MDA-7, MOB-5, ST16) |
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| Description | Purity ~95% (SDSPAGE). Interleukin 24 (IL24), also known as FISP (IL4 induced secreted protein) in mouse, and mda7 (melanoma differentiation associated gene7) in humans, is a member of the IL10 family of helical cytokines (13). The mouse IL24 gene encodes for a 181 amino acid (aa) precursor that includes a 26 aa signal sequence and an 18kD (predicted), 155 aa mature segment (4). Unlike mature human IL24, which contains three potential Nlinked glycosylation sites, mouse mature IL24 has only one. In human, both glycosylation and the presence of an intrachain disulfide bond have been found to be necessary for full activity (5). This requirement for glycosylation is unique among IL10 family members. Presumably, the same structural modifications apply to mouse IL24. Mouse IL24 is a 27kD protein when secreted, and is active on human receptors (1, 3). Mature mouse IL24 shares 69%, 84%, 69%, 68% and 61% aa sequence identity with human, rat, equine, canine and bovine IL24, respe |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145706 |
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| Order / More Info | IL-24, Recombinant, Mouse, aa66-220 (Interleukin 24, C49A, FISP, MDA-7, MOB-5, ST16) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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