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| Product Name | IL-6, Recombinant, Mouse,Fc (Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1) |
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| Description | Purity >95% (SDS-PAGE). Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kD-28kD phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells. Biological Activity: Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml. Sequence: The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44950 |
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| Order / More Info | IL-6, Recombinant, Mouse,Fc (Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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