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| Product Name | Il13, Recombinant, Rat (Interleukin-13, IL-13, T-cell Activation Protein P600, Il-13) |
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| Description | Purity ~98% (SDS-PAGE and HPLC). IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1b, TNF-a, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant rat IL-13 is a 12.3kD protein consisting of 113aa. Source: Recombinant protein corresponding to rat IL-13, expressed in E.coli. Biological Activity: Determined by the dose-dependent proliferation of TF-1 cells. The ED50 was found to be <5ng/ml. Specific Activ |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149716 |
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| Order / More Info | Il13, Recombinant, Rat (Interleukin-13, IL-13, T-cell Activation Protein P600, Il-13) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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