| 产品详情 |
| Edit |   |
|---|
| Product Name | IL-2 Receptor alpha, Recombinant, Human (IL2RA, Soluble IL-2 receptor, TAC-antigen, CD25 antigen) |
|---|
| Description | Purity ~98% (SDS-PAGE). The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ra, IL-2Rb, and IL-2Rg. The IL-2Ra is a type I transmembrane protein consisting of a 219aa extracellular domain, a 19aa transmembrane domain and a 13aa intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2Ra releases the entire extracellular domain of IL-2Ra thereby generating a 219aa soluble protein called soluble IL-2Ra (sIL-2Ra). The homodimeric form binds IL-2 (KD=10mM) and facilitates IL-2 signaling. The secreted sIL-2Ra is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells. Source: Recombinant protein corresponding to human IL-2 Receptor alpha, containing 219aa residues consisting of only the extracellular domain, expressed in (BTI-Tn-5B1-4) Hi-5 Insect Cells. Molecular Weight: ~24.8kD (~31kD on SDS-PAGE due to glycosylation) Biological Activity: D |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | soluble IL-2 receptor, TAC-antigen, CD25 antigen |
|---|
| Gene, Accession, CAS # | IL2RA, Gene ID: 3561, SwissProt: P31785 |
|---|
| Catalog # | 219925 |
|---|
| Price | |
|---|
| Order / More Info | IL-2 Receptor alpha, Recombinant, Human (IL2RA, Soluble IL-2 receptor, TAC-antigen, CD25 antigen) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|