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| Product Name | Dectin 2, Recombinant, Human (CLEC6A, CLECSF10, NKCL) |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE and visualized by silver stain. Dectin-2, also known as CLEC6A, CLECSF10, and NKCL, belongs to the C-type lectin family of transmembrane immune regulatory glycoproteins. Dectin-2, plus CLEC4A-E constitute a subgroup of molecules that exhibit approximately 40% aa sequence identity in their extracellular domains (ECD), and have a conserved cysteine spacing in their carbohydrate recognition domains (CRD) (1, 2). Mature human Dectin-2 is a type II transmembrane protein with a short cytoplasmic tail, a transmembrane segment, and a 168 aa ECD with a stalk region and one CRD (3, 4). Within the ECD, human Dectin-2 shares 71% and 75% aa sequence identity with bovine and mouse Dectin-2, respectively. An alternately spliced β isoform has a deletion of portions of the transmembrane and cytoplasmic regions (5). Full length Dectin-2 is a 27 kD molecule that is expressed on monocytes, tissue macrophages, and activated CD4+ T cells (4-6). The CRD of Dectin- |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q6EIG7 |
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| Catalog # | D1876-50 |
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| Order / More Info | Dectin 2, Recombinant, Human (CLEC6A, CLECSF10, NKCL) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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