| 产品详情 |
| Edit |   |
|---|
| Product Name | Tumor Necrosis Factor Receptor Superfamily Member 5 (CD40) BioAssay™ ELISA Kit (Mouse) |
|---|
| Description | This protein is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Sample Type: Serum, plasma, tissue homogenates Intended Use: For the quantitative determination of mouse Tumor necrosis factor recep |
|---|
| Size | 48 tests, 96 tests, 24 tests |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: P27512 |
|---|
| Catalog # | 351727 |
|---|
| Price | |
|---|
| Order / More Info | Tumor Necrosis Factor Receptor Superfamily Member 5 (CD40) BioAssay™ ELISA Kit (Mouse) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|