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| Product Name | Fenobam (N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea) |
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| Description | Purity ~98% (HPLC). A potent negative allosteric modulator highly selective for mGluR5 (IC50 = 87nM; Kd = 54nM and 31nM at recombinant mGlu5 receptors of rat and human, respectively). Biologically active admitted orally or systematically. Frequently used for assessing the functional roles of mGlu5 receptors in a variety of brain functions (i.e. learning and memory, circadian rhythms, reward and decision making, and locomotion) and disorders (i.e. addition, depression, seizures, anxiety disorder, Parkinsons disease, Alzheimers disease, and Down syndrome). A leading therapeutic candidate for treatment of fragile X syndrome. Formula: C11H11ClN4O2 Primary Target: mGlu5 receptors Primary Target IC50: 87nM Primary Target Ki: 54nM and 31nM at recombinant mGlu5 receptors of rat and human, respectively. Solubility: DMSO |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217356 |
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| Order / More Info | Fenobam (N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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