| 产品详情 |
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| Product Name | PYCR1, aa1-319, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant protein corresponding to human PYCR1, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~35.5kD (339aa), confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSVGFIGAGQ LAFALAKGFT AAGVLAAHKI MASSPDMDLA TVSALRKMGV KLTPHNKETV QHSDVLFLAV KPHIIPFILD EIGADIEDRH IVVSCAAGVT ISSIEKKLSA FRPAPRVIRC MTNTPVVVRE GATVYATGTH AQVEDGRLME QLLSSVGFCT EVEEDLIDAV TGLSGSGPAY AFTALDALAD GGVKMGLPRR LAVRLGAQAL LGAAKMLLHS EQHPGQLKDN VSSPGGATIH ALHVLESGGF RSLLINAVEA SCIRTRELQS MADQEQVSPA AIKKTILDKV KLDSPAGTAL SPSGHTKLLP RSLAPAGKD Specific Activity: ~0.03unit/mg Biological Activity: One |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PYCR1, aa1-319, Recombinant, Human (Pyrroline-5-carboxylate Reductase 1, P5C Reductase 1, P5CR 1, ARCL2B, P5C, P5CR, PIG45, PP222, PRO3, PYCR) |
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| Gene, Accession, CAS # | Accession: NP_008838 |
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| Catalog # | P9399-25 |
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| Order / More Info | PYCR1, aa1-319, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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