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| Product Name | TAF1 (BD1), Recombinant, Human, aa1400-1518, His-Tag (TBP-Associated Factor) |
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| Description | Highly Purified (~95%). Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004606, SwissProt: P21675 |
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| Catalog # | 298467 |
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| Order / More Info | TAF1 (BD1), Recombinant, Human, aa1400-1518, His-Tag (TBP-Associated Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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