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| Product Name | Synuclein, gamma CT Control Peptide (BCSG1, SYN) |
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| Description | 18-aa peptide near the C-terminus of rat g-synuclein. The rat peptide sequence is 100% conserved in mouse g-synuclein. No significant sequence homology is seen with either human g-synuclein or synucleins-alpha or beta) or other proteins. Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important and initial step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 aa peptides (beta amyloid1-40, 1-42, and 1-43). Polymerization of b-amyloid (Ab) and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. Ab deposits have also been found to contain 2 additional proteins termed a-synuclein and b-synuclein. The 140 aa a-synucleins is identical with non-Ab component (NACP) of AD. The 134 aa b-synuclein is homologous to 14kD bovine phosphoneuroprotein 14. Mutations in a-synuclein gene causi |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | S9502-05P |
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| Order / More Info | Synuclein, gamma CT Control Peptide (BCSG1, SYN) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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