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| Product Name | MSTN, Recombinant, Human (MSTN, Growth Differentiation Factor 8, GDF-8, Myostatin) |
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| Description | Purity ~95% (SDS-PAGE). Growth differentiation Factor 8 (GDF-8), also known as myostatin, is a secreted protein that is expressed specifically in developing and adult skeletal muscle. It controls myoblast proliferation and is a potent negative regulator of skeletal muscle mass. GDF-8 belongs to the transforming growth factor beta (TGF-beta) superfamily, which includes the TGF-betas, bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs), activins, inhibins, leftys, nodal, Mullerian inhibitory substance (MIS) and the glial cell line-derived neurotrophic factors (GDNFs). All TGF-beta superfamily members are synthesized and secreted as a homodimeric prepropeptide that is cleaved by proprotein convertases such as furin to generate the dimeric N-terminal propeptide and the dimeric C-terminal mature active protein. The C-terminal mature protein contains the characteristic conserved cysteine residues involved in the formation of the cysteine knot domain. Mouse GDF-8 cDNA encodes a 376aa residue pr |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O14793 |
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| Catalog # | 500286 |
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| Order / More Info | MSTN, Recombinant, Human (MSTN, Growth Differentiation Factor 8, GDF-8, Myostatin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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