| 产品详情 |
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| Product Name | MST3, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). MST3 or Mammalian Sterile 20-like kinase 3 is a member of the germinal center kinase-III family. MST3 contains a conserved kinase domain at its NH-terminal and a regulatory domain at its COOH-terminal Caspase-mediated cleavage of the regulatory domain of MST3 activates its intrinsic kinase activity and leads to nuclear translocation. Expression of COOH-terminal truncated MST3 in cells results in DNA fragmentation and induction of apoptosis. MST3 can inhibit cell migration in a fashion dependent on autophosphorylation and can regulate paxillin phosphorylation through tyrosine phosphatase PTP-PEST. Source: Recombinant protein corresponding to human MST3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~63kD Specific Activity: 265nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MST3, Recombinant, Human, GST-Tag (Mammalian Sterile 20-Like Kinase 3, STK24, MST-3, STK3, MST3B, RP11-111L24.5) |
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| Gene, Accession, CAS # | Accession: NM_001032296 |
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| Catalog # | 500284 |
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| Order / More Info | MST3, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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